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br Acknowledgements br Funding This work was supported
2022-01-04
Acknowledgements Funding: This work was supported by the Instituto Nacional de Biomedicina do Semiárido (INCT-IBISAB-CNPq), Edital MCT/CNPq N° 014/2010 - Universal and Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES). Introduction Guanylin and uroguanylin are small, heat-
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While a role for YAP TAZ signaling
2022-01-04
While a role for YAP/TAZ signaling in oligodendrocytes has not been described, these SB 265610 are also responsive to mechanical stimuli. OPC proliferation and migration can be altered by plating on substrates of varying stiffness [20], resulting in differentiation in a density-dependent manner. Pla
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In order to investigate whether this
2022-01-04
In order to investigate whether this off-target activity was related to a particular structural feature of this 8-Azido-ATP mg or was characteristic of the series, compounds , and were selected as being matched pairs with compound but with structural variation in terms of the R, R and R groups,
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br Materials and methods br Results br Discussion All the
2022-01-04
Materials and methods Results Discussion All the UDG superfamily glycosylases examined here, UDG, SMUG1, TDGFL, and TDG82−308, are capable of completely converting U-containing duplex substrates to product, though at different rates. Under STO conditions, kobs reflects the slowest kinetic s
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The aims of the present study were to
2022-01-04
The aims of the present study were to further investigate the localisation of glycine and GABAA receptors on individual neurons and how closely these two receptor types were associated with each other by carrying out double immunofluorescent labelling and imaged using confocal laser scanning microsc
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EAAT glutamate uptake is driven
2022-01-04
EAAT glutamate uptake is driven by the co-transport of three sodium ions and one proton, as well as the counter-transport of one potassium ion (Fig. 1B). This complex stoichiometry frees up enough energy to permit Alrestatin of glutamate into the cell against a steep concentration gradient. Addition
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Because of the relationship between carbohydrate consumption
2022-01-04
Because of the relationship between carbohydrate consumption and chronic diseases such as obesity and type II diabetes (Hu, van Dam, & Liu, 2001), there is mounting interest to evaluate the quality of Epirubicin HCl synthesis through analysis by glycemic index (GI) and Englyst assay, for example (E
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In the present study Trichoderma
2022-01-04
In the present study, Trichoderma viride β-glucosidase was screened in our laboratory and used for the synthesis of gentiooligosaccharides via reverse hydrolysis and transglycosylation. Material and methods Results and discussion Conclusions In the present study, the T. viride β-glucosidas
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L Family Leguminosae widely distributed in
2022-01-04
L. (Family Leguminosae) widely distributed in tropical and subtropical regions of the world. As a medicinal and edible plant, it is widely used in Asia, especially in China, Korea, Japan and India. It was first recorded in Shen Nong Ben Cao Jing (神农本草经), and was described having the effect of cleari
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The energy required to drive
2022-01-04
The energy required to drive the functional process to actively maintain lens transparency is primarily derived from the metabolism of glucose. Since the lens is avascular and exists in an environment of low oxygen tension, glucose is primarily metabolized by PPACK Dihydrochloride glycolysis (Kinos
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Next we studied the effects
2022-01-04
Next, we studied the effects of the compounds PA-Glu, PA-hSuc, and PA-hPim on the IGly of rat hippocampal neurons. As in the experiments with IGABA, IGly was affected by steroids with a pregnane skeleton, but not those with an androstane skeleton. At the same time, androstane steroids were shown to
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br STAR Methods br Acknowledgments We would like to
2022-01-04
STAR★Methods Acknowledgments We would like to thank V. Gladyshev (Harvard), H. Kornblum (UCLA), L. Greene (Columbia), and J. Baraban (Johns Hopkins) for constructive comments to the project and manuscript. We thank L. Gross and A. Kumar for assistance with editing. We thank L.M. Gerber and Z.
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br Conclusions According to our
2022-01-04
Conclusions According to our results we may suggest that FAS c.-671AG Senexin A or G allele and FASLG gene c.-844T allele were not to be a risk factor, whereas FASLG gene c.-844TC genotype may be protective in the studied Turkish population. Because of the limited sample size in this study, furth
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Depletion of PI P e g
2022-01-04
Depletion of PI(4,5)P2, e.g. by knockout of PIPKIγ, also profoundly inhibits SV endocytosis (Di Paolo et al., 2004). Conversely, loss of the PI(4,5)P2-metabolizing PI-phosphatase synaptojanin or its recruitor endophilin stalls SV recycling at the level of clathrin-coated vesicles (Bai et al., 2010,
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Ketorolac tromethamine salt br Acknowledgments The authors
2022-01-03
Acknowledgments The authors gratefully acknowledge the financial support of this study by STCU Project 6052 “Enzyme multibiosensor system for renal dysfunction diagnosis and hemodialysis control”. Furthermore, this study was supported by NASU in the frame of Scientific and Technical Program “Sens
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