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Afterward Fluc hNIS mMABs were
2018-11-09
Afterward, Fluc-hNIS+ mMABs were bilaterally injected into the femoral polo like kinase and successfully monitored via both BLI and small-animal PET. After systemic administration, we were clearly able to monitor mMABs for several days via small-animal PET. Long-term cell monitoring was not feasibl
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Accumulating evidence indicates that treatment using extrace
2018-11-09
Accumulating evidence indicates that treatment using extracellular vesicles (EVs) have multiple advantages over cell therapy, because EVs are stable in the circulation without losing function and exhibit a superior safety profile (Vader et al., 2016). In particular, MSCs are an attractive source of
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GLPG0634 Thus the calculated Navier Stokes equations for an
2018-11-09
Thus, the calculated Navier–Stokes equations for an incompressible conducting fluid which include the density of the EM field force as the driving force can be expressed in the following way in differential form: Here μ is the effective viscosity, defined as the sum of the laminar and the turbule
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Considering the role of the environment and
2018-11-09
Considering the role of the environment and gut microbiome in the pathobiology of the disease (Li and Jia, 2013; Wilson, 2009), a “pharmacometabolomics-aided pharmacogenomics” strategy could be of great benefit, as pharmacogenomics alone fails to address environmental influences. Taking into account
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br Materials and Methods br Results Overall of the TNP
2018-11-09
Materials and Methods Results Overall, 17·0% of the TNP and 23·5% of the LMNP fly specimens were positive for T. pallidum DNA (Table 1). Not all samples were positive or were tested for all three loci (Tables 1 and 2, and Table S2). The polA PCR reaction was positive less frequently than the d
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retinoid x receptor br Materials and Methods br Results br
2018-11-09
Materials and Methods Results Discussion Psoriasis is a chronic systemic inflammatory and an autoimmune skin disease. It is histologically characterized by KC hyperproliferation, inflammation, and increased angiogenesis (Bachelez, 2005; Nestle et al., 2009). Although considerable progress i
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br Funding Sources This work was funded
2018-11-09
Funding Sources This work was funded through institutional support from INSERM and by the Agence Nationale pour la Recherche (ANR Blanc 2011, No.: 11-BSV1 005 03, ANR-13-ISV1-0006-01), the Fondation pour la Recherche Médicale (DEQ20140329556), the Programme Hospitalier de Recherche Clinique (PHRC
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aa-dutp Our assumptions are all conservative and our results
2018-11-09
Our assumptions are all conservative and our results are robust to variance on the dimensions of uncertainty as demonstrated in Table 4. Our estimates understate the DALYs gained from each device in that they don’t include the health benefits to the unborn child from improved diagnosis of pre-eclamp
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As some of the material
2018-11-09
As some of the material in this review is speculative, it is worth being more concrete about specific lines of research to follow up on our suggestions. First, it would be important to establish whether there is indeed a developmental moderation of risk for SAD. More precisely, here, we make the sug
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El Cuadro en su primera columna enumera los diferentes
2018-11-09
El Cuadro 3 en su primera columna enumera los diferentes diseños, la segunda, tercera y cuarta señala en términos binarios que característica presenta cada componente. En la quinta columna se da un valor de desempeño a cada batería (que puede representar algún parámetro como densidad de energía), en
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Escalarmente el ttp es parte de
2018-11-09
Escalarmente, el ttp es parte de la contra tendencia capitalista mek inhibitors un doble proceso de re-territorialización y desterritorialización; es decir, al proceso tendencialmente expansivo del capitalismo, expresado en la escala supranacional de la globalización, se corresponde una contra tende
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In the present study we investigated a well
2018-11-09
In the present study, we investigated a well-defined and selected group of NF1 patients fully active in daily life, with normal intelligence and without motor or cognitive impairments carrying the NF1 mutation and compared them to age-matched controls. Participants were investigated over an extended
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br Methods CHC patients receiving anti viral therapy
2018-11-09
Methods CHC patients receiving anti-viral therapy were consecutively recruited as a prospective follow-up cohort at one tertiary hospital and two core regional hospitals from 2002 to 2012. All the participants received peginterferon alpha-2a or peginterferon alpha-2b plus ribavirin. Patients were
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Our results also appear to be in
2018-11-08
Our results also appear to be in line with earlier observations that ABCG2 expressing cells are overall smaller than cells positive for CK3 (de Paiva et al., 2006; Kim et al., 2004). As to the effect of oxygen, it is interesting to note that both the ABCG2+ and CK3+ were in general larger in sub-amb
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One of the main obstacles in human studies
2018-11-08
One of the main obstacles in human studies is sample acquisition. Human iPSC lines are usually produced from fibroblasts isolated from skin biopsies, a traumatic invasive procedure demanding local anesthesia and medical follow-up. Hair follicle (HF) plucking, however, is simple, painless and non-inv
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