• Introduction Cancer therapy has evolved throughout the decad

  2019-06-17

  

  Introduction Cancer therapy has evolved throughout the decades and is beginning to branch off into new and exciting fields including immunotherapy. The hope of this new field stems from the lack of success of chemotherapy in general. Chemotherapy\'s cytotoxic characteristics were regarded as one of

• br Conflict of interest br

  2019-06-17

  

  Conflict of interest Acknowledgment Introduction The majority of clot embolisms associated with atrial fibrillation (AF) are from the left atrial appendage (LAA). Before cardioversion or catheter ablation, clot formation needs to be ruled out traditionally using transesophageal echocardiogr

• Adequate nutritional support for pregnant

  2019-06-15

  

  Adequate nutritional support for pregnant women is an important issue, not only to help such women maintain peak health and performance, but also as it indirectly affects fetal growth and the minimization of adverse fetal outcome risks. Among those nutritional components that are integral to this su

• mps1 The cardiac GP are a collection of autonomic nervous sy

  2019-06-15

  

  The cardiac GP are a collection of autonomic nervous systems comprising both afferent and efferent as well as sympathetic and parasympathetic fibers [10,11]. Radiofrequency catheter ablation eliminates the most elementary level of vagal innervation by destroying the visceral efferent limb of the par

• Cerrone et al reported that the mechanism of

  2019-06-15

  

  Cerrone et al. reported that the mechanism of CPVT was due to delayed afterdepolarization‐induced triggered activity in a focal Purkinje network in a knock-in (RyR2) mouse [36]. In addition, chemical ablation of the RV endocardial cavity with Lugol׳s solution, which selectively destroys the Purkinje

• br Interpretation of identified genetic variants

  2019-06-15

  

  Interpretation of identified genetic variants and genetic counseling Although the current expert consensus statement recommends that comprehensive or BrS1 (SCN5A) targeted BrS genetic testing can be useful for genetic testing [63], not all the published SCN5A mutations in BrS have been subjected

• What would mitigation strategies to deal

  2019-06-15

  

  What would mitigation strategies to deal with future pandemic risks of zoonotic disease look like? Analyses of emerging disease trends during the past six decades have shown that Ebola fits the CYC202 pattern. This pattern involves zoonotic spillover from wildlife or livestock driven by changes in l

• Interpretation Stakeholders from sectors not historically en

  2019-06-14

  

  Interpretation Stakeholders from sectors not historically engaged in health care are forming unique partnerships with common goals and a willingness to address the challenge of global cancer care. Funding None. Declaration of interests Abstract Background Since 2013 medical students from Nort

• By showing the great variability in surgical

  2019-06-14

  

  By showing the great variability in surgical outcomes across LMICs, Uribe-Leitz and colleagues have shared with the world instructive knowledge that aids our ongoing advocacy efforts to promote quality in surgical care in resource-limited settings. Ultimately, for destitute sick and injured patients

• pgi2 HF is associated with the down regulation

  2019-06-14

  

  HF is associated with the down-regulation of multiple potassium (K) currents (i.e., Ito, IKs, IKr, IK1, and IKATP). The only K channel that is upregulated in HF is the small conductance Ca-activated K (SK) channel. The SK channel was originally found in most neurons. The increase in Cai evoked by th

• phospholipase a2 inhibitor The tumor microenvironment is enr

  2019-06-14

  

  The tumor microenvironment is enriched with EMVs that are derived not only by proliferating tumor cells, but also from infiltrating macrophages and neutrophils, and support tumor cell survival, growth, invasion and metastasis. Tumor derived EMVs also have the potential to modulate surrounding stroma

• br Hybrid approach It is

  2019-06-14

  

  Hybrid approach It is still not certain whether a single or a staged approach is safer and more effective. Natale et al. [31] performed a combined closed-chest epicardial monopolar radiofrequency ablation through a transabdominal transdiaphragmatic single port and catheter-based transseptal endoc

• The BrS ECG is often widely dynamic

  2019-06-14

  

  The BrS ECG is often widely dynamic, with ST segment elevations that fluctuate from hour to hour, day to day, and month to month. Diurnal variation shows that events occur more frequently at night during periods of high vagal tone [2]. In some patients, the use of frequent ECGs or 12-lead ambulatory

• We moreover confirmed previous evidence of a net increase

  2019-06-14

  

  We, moreover, confirmed previous evidence of a net increase of CT density of bone metastases after ZA treatment and demonstrated that the changes persist at a 24 months follow-up. This study and previous reports [24–26] have demonstrated significant sclerotic changes of BMs, more evident in patients

• Pese a su evidente inter

  2019-06-14

  

  Pese SL-327 su evidente interés a nivel de hipótesis, el plan original de Pay-no no tuvo por qué descarriarse como proyecto literario. Al contrario, el intento por parte de Payno de representar en su novela el desastre nacional ocurrido en la capital de México a partir de la ocupación norteamericana

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