• The following are the supplementary data related to this

  2018-10-29

  

  The following are the supplementary data related to this article. Acknowledgments We thank Kersti Jääger and Angelika Fatkina for their help in flow cytometry experiments. We are very thankful to Dr. Sirje Rüütel Boudinot, Dr. Marko Piirsoo and Jekaterina Kazantseva for valuable comments and dis

• We have demonstrated also in this

  2018-10-26

  

  We have demonstrated also in this study that inhibition of the cellular antioxidant mechanism could promote differentiation of GICs. We also observed that GICs have an enhanced antioxidant mechanism compared to their serum-differentiated counterparts. Based on these findings, we speculate that GICs

• These insights into the HSC independent versus HSC dependent

  2018-10-26

  

  These insights into the HSC-independent versus HSC-dependent immune cell reconstitution pathway in mice can be expected to affect protocols used for HSC transplantation in clinical settings. Over the past 45 years, HSC transplantation has been widely used to treat patients with cancers such as leuke

• br Experimental Procedures br Introduction Cells have been r

  2018-10-26

  

  Experimental Procedures Introduction β Cells have been reported to have the potential to proliferate after experimental ablation, such as chemical treatment or partial pancreatectomy (Bonner-Weir et al., 2010) (Cano et al., 2008; Nir et al., 2007; Xu et al., 2008). Although controversial, β ga

• sphingosine br Experimental Procedures br Author Contributio

  2018-10-26

  

  Experimental Procedures Author Contributions Acknowledgments Introduction Tissue engineering technology has become one of the most promising therapeutic approaches for bone regeneration in bone defects (Zou et al., 2011; Ye et al., 2011; Xiao et al., 2011). As a source of mesenchymal ste

• Mosaicism in CGG repeat length is often observed

  2018-10-26

  

  Mosaicism in CGG repeat length is often observed in FXS patients, who carry both premutation and full mutation metabotropic receptors and therefore differ in the proportion of cells with silenced FMR1, which contributes to the clinical spectrum of FXS phenotypes (Rousseau et al., 1994). Mosaicism in

• Although we have investigated in

  2018-10-26

  

  Although we have investigated in detail the differentiation of bone marrow-derived MSCs, further in-depth studies are needed to establish whether MSCs from adipose tissue or different anatomical locations undergo a similar cascade of transcriptional events. Although adipose-derived MSCs could functi

• In addition stigma experienced by the study

  2018-10-26

  

  In addition, stigma experienced by the study participants can explain the low rate and inverse effect of herpes simplex virus 2 participation. Stigma against PLWH is a known barrier to accessing HIV testing and care. Perceived stigma negatively affects the quality of life (QoL) of PLWH (Holzemer et

• br Sleep study A Type

  2018-10-26

  

  Sleep study A Type III home sleep study was performed using Embletta Portable Diagnostic System (Stowood Scientific Instruments, Oxford UK) and Somnologica software (Embla, Broomfield, USA) for analysis, due to the comparability in diagnosing adult patients with a high probability of moderate to

• br Problem solved By the

  2018-10-26

  

  Problem solved By the time Wicksell wrote his 1900 article on marginal productivity and volume 1 of his Lectures (preface dated February 1901), it became clear that the main issue involving the machinery question was not empirical, but theoretical. If correct, the notion that a viable technical c

• Chart presents a summary of these studies

  2018-10-25

  

  Chart 1 presents a summary of these studies. These, given their important findings and results, corroborate the assertion of Haddad (2007) on the importance of computable general equilibrium models for the exercise of simulations of economic environments, and for the implementation of economic polic

• There remains controversy however as to

  2018-10-25

  

  There remains controversy, however, as to the precise mechanism of genesis of such phenotypes (Cieslewicz et al., 1999). One of the major stumbling blocks here is lack of data concerning the kinetics of lung granulocyte immigration and emigration in asthma. Studies addressing the differential migrat

• Mature miRs act by destabilising mRNAs with some degree

  2018-10-25

  

  Mature miRs act by destabilising mRNAs with some degree of complementarity or by repressing protein translation, leading to down regulation of target genes and changes in biological functions (Bohnsack et al., 2004; Chen and Rajewsky, 2007; Kim, 2005; Lee et al., 2003). The expression of miRs is tig

• In spite of these interesting observations

  2018-10-25

  

  In spite of these interesting observations, some additional questions arise from the study. For example, consistent with previous reports, circadian phase and period length are influenced by diet (). However, here the HFD has the general effect in WT mice of shortening period length rather than leng

• The estimates of cancer free survival for the

  2018-10-25

  

  The estimates of cancer-free survival for the groups with 10-min adenylate cyclase levels below and above the median showed an increasing divergence over the 40-year follow-up (Fig. 2). Thus, it is unlikely that causal factors related to glucose disposal at baseline were temporary in nature. It is

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