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There are a number of reasons that make the
2018-10-30
There are a number of reasons that make the possibility to use blood-based miRNA signatures as diagnostic tools very attractive: i) cancer can be diagnosed in a minimally invasive way through a simple blood test; ii) a blood test does not require hospitalization and the access to complex and expens
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A multi biomarker based outcome stratification model
2018-10-30
A multi-biomarker based outcome stratification model has also been advocated by Wong et al. that reliably estimated probability of mortality based on inflammatory markers along with conventional clinical and demographic data. Similar to our approach the sensitivity is much better than the specificit
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Increasing globalization in travel and trade will
2018-10-30
Increasing globalization in travel and trade will intensify the importation of dengue viruses and the potential for further introduction of Ae. aegypti (Gubler and Clark, 1995). If such introductions coincide with suitable vectorial capacity, those cities at the time intervals identified in this stu
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A correct NF diagnosis has important implications
2018-10-30
A correct NF1 diagnosis has important implications for prognosis, counseling, and prenatal diagnosis. Molecular diagnosis in NF1 is helpful to confirm the clinical diagnosis, notably in patients with paucisymptomatic, pediatric, or segmental presentations. In young children, café-au-lait macules are
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fluvastatin We also show that recruitment of MUS EME is requ
2018-10-30
We also show that recruitment of MUS81-EME1 is required for SLX4com-mediated control of pro-inflammatory signaling. This suggests that, similar to what was previously reported for HIV biology (Laguette et al., 2014), the SLX4com likely represses LINE-1 retrotransposition through the endonucleolytic
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br The Nkx factors are a family
2018-10-30
The Nkx factors are a family of homeodomain containing transcription factors known to have tissue specific Quizartinib Supplier and thought to play a regulatory role in organ development. Certain members of this family have been studied in detail and found to play a role in disease. For example,
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Because only transient exposure of melanoma cells to pevoned
2018-10-30
Because only transient exposure of melanoma NHS-LC-Biotin manufacturer to pevonedistat is sufficient to irreversibly arrest melanoma cells with the majority of cells undergoing senescence, and this occurs only in malignant melanoma cells, targeting the CRL4CDT2 ubiquitin ligase is an especially attr
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To prevent the negative impact of hemolysis the
2018-10-30
To prevent the negative impact of hemolysis, the U.S. Food and Drug Administration set the upper threshold of hemolysis in a RBC unit to be transfused at 1% but some RBC units stored under standard blood banking conditions fail to meet this requirement due to factors that may be donor specific (Mish
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cpi-613 br Data These data mainly focus on
2018-10-29
Data These data mainly focus on the dose-dependent neuroprotection provided by baclofen, memantine and l-carnitine against oxygen-glucose-deprivation (OGD)-related neurodegeneration of CA1 region, with an addition of the data obtained from the use of hypothermia instead of pharmacological agents.
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The authors also suggest that there is an interviewer gender
2018-10-29
The authors also suggest that there is an interviewer gender effect in key violence indicators. That is the case when using FTFI and asking about whose prevalence is lower than that among men interviewed by men. Regarding FTFI method and in agreement with previous studies (Davis et al., 2010), it
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br Discussion BPDCN is an
2018-10-29
Discussion BPDCN is an aggressive, rare hematologic neoplasm that mainly affects elderly individuals 60 to 70 years of age, with a male predominance and a median survival of 12–16 months. Most patients present with multiple nonpruritic cutaneous lesions followed by involvement of the lymph nodes,
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Tambi n fueron publicadas algunas peque as citas de
2018-10-29
También fueron publicadas algunas pequeñas citas de autoras como María Elena Walsh. Por ejemplo, en el primer número, se transcribieron unas reflexiones en las que confluye naturalmente la preocupación de la lucha feminista en el marco del contexto político y cultural de Argentina de los setenta. S
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Por supuesto detr s de
2018-10-29
Por supuesto, detrás de la oleada de reformas constitucionales estatales en México existen grupos y sociedades cristianas —comenzando por la misma Iglesia católica—, las cuales han participado y participan de manera activa en su implementación. Esto en sí mismo no es censurable. Lo que sí lo es, es
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used by Muchas feministas coincidieron con Barry en su
2018-10-29
Muchas feministas coincidieron con Barry en su planteamiento en Esclavitud sexual de la mujer (1979), donde sostiene que los valores que las mujeres siempre le han atribuido used by la sexualidad habían sido distorsionados y destruidos conforme habían sido “colonizadas” a través tanto de la violenc
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Por eso como lo documentaron Lexartza et al las
2018-10-29
Por eso, como lo documentaron Lexartza et al. (2013), las violencias feminicidas de las que huyen las centroamericanas se suman al uso que se hace de sus cuerpos como testimonio de la barbarie que puede ejercerse entre los bandos que se disputan un territorio. Tal y como contaba Diana, migrante hond
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