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Currently there are no medications or modalities to
2018-11-13
Currently, there are no medications or modalities to reduce both visceral adiposity as well as chronic inflammation in MS or T2DM subjects. Recently, we (Morino et al., 2008a; Adachi et al., 2010) and others (Chung et al., 2008; Gupte et al., 2009) have shown that the beneficial metabolic advantages
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br Introduction Type diabetes T D affects million
2018-11-13
Introduction Type 2 diabetes (T2D) affects 380 million individuals worldwide, and its prevalence will further increase in the coming decades with the obesity epidemic (IDF Diabetes Atlas, 2013). T2D is characterized by progressive loss of pancreatic β cell function and insulinopenia, and by non-s
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Treatment of acquired TTP involves plasma exchange PEX to pr
2018-11-13
Treatment of acquired TTP involves plasma exchange (PEX) to provide a new source of ADAMTS13. Steroids are used to target the autoimmune component of the disease. Therapy with rituximab reduces rates of recurrence (Scully et al., 2011; Westwood et al., 2013). Recombinant ADAMTS13 is currently underg
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FASN plays a critical role in
2018-11-13
FASN plays a critical role in a number of metabolic functions by catalyzing the terminal steps in the synthesis of long-chain saturated fatty acids. There is a strong FASN expression and high enzymatic activity in many cancers especially in carcinomas (), while FASN is expressed at low levels in mos
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Notably in psoriatic patients the presentation of schizophre
2018-11-12
Notably, in psoriatic patients, the presentation of schizophrenia is more prevalent in women and those aged > 40-years. Generally, schizophrenia is more common in men than in women, with a ratio of 1.4:1, and women tend to experience disease onset in older age. In women, there is a peak occurrence b
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The uncertainty in the measurement of the
2018-11-12
The uncertainty in the measurement of the projectile tip position is mainly caused by the resolution of the radiographical and optical system and the fact that, at material edges and interfaces, a gradual transition of gray shades occurs. These influences led to an uncertainty in the position measur
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The influence of the fracture toughness
2018-11-12
The influence of the fracture toughness of the ceramic material on the transition pressure is illustrated in Fig. 8. Experimentally determined as well as estimated transition velocities and pressures versus prestress are shown in Fig. 9. Unless otherwise stated, the material data for SiC-B in Table
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Actually there was more attention to the effect of
2018-11-12
Actually, there was more attention to the effect of CsA on GO that have been clearly demonstrated. Hence, in this investigation we tried also to focus on TAC as well. To our knowledge this comparative immune-histochemical investigation using this group of cytokines has been not previously attempted
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IoT may be defined as
2018-11-12
IoT may be defined as “A global infrastructure for the information society enabling advanced services by interconnecting (physical and virtual) things based on, existing and evolving, interoperable information and communication technologies” [37]. The definition of “Cloud” is presented as prescribed
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br Conclusion br Acknowledgments br Introduction A baumannii
2018-11-12
Conclusion Acknowledgments Introduction A. baumannii is a leading cause of nosocomial bacteremia, severe pneumonia, meningitis, infections of the urinary tract, bloodstream and other parts of the body. The emergence of sharply increasing rate of Multidrug-resistant A. Baumannii (MDRAB) infe
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br The stone sail With regards to environmental
2018-11-12
The “stone sail” With regards to environmental and technological performance, it must be taken into consideration that the components being assembled dry promote the assembly and subsequent disassembly with full recovery of all elements. They, once disassembled, can be recycled or reused for othe
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Another challenge for architects facility managers and inter
2018-11-12
Another challenge for architects, facility managers, and interior designer is integrating a design specification that relates to the sense of home into a design of nursing homes, which is often based on dementia-friendly design models. Zeisel (2005), among other scholars, stated that several dementi
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The statue of the famous emperor Marcus Aurelius
2018-11-12
The statue of the famous emperor Marcus Aurelius was, in fact, the centerpiece of Michelangelo׳s piazza on the Capitolium. In 1538, Pope Paul III moved the statue here from S. Giovanni in Laterano (i.e., the basilica of S. John at the Lateran) where it stood for centuries and was miraculously preser
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br Urban context The building
2018-11-12
Urban context The building of Rome׳s university campus, between 1930 and 1935, represented a complicated and problematic process that cycloastragenol was deeply intertwined with Italian history. Many cultural transformations took place at that time, particularly in the architectural profession,
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When application of simple public address system based
2018-11-12
When application of simple public address system based on the electro acoustics installed at the cathedral, improved sound pressure and clarity (SPL, C80, D50, ITDG, and RASTI were improved significantly, excluding reverberation characteristics) can be acquired as follows: SPL (74.5 dBA on average),
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