• br Results br Discussion We report

  2018-11-14

  

  Results Discussion We report the development of a method to generate and proliferate iCx26GJCs from mouse iPSCs for use as a disease model and in inner-ear cell therapies targeting GJB2-related hearing loss, the most frequent type of hereditary deafness worldwide. Our induction method until da

• Introduction In the first commercial inductively coupled pla

  2018-11-14

  

  Introduction In 1984, the first commercial inductively coupled plasma mass spectrometry (ICP-MS) appeared, soon after that, Gray (1985) analyzed the elemental and Pb isotopic compositions of granites by combining ICP-MS and laser ablation (LA), thereby initiating the application of LA-ICP-MS in the

• In the present study the sensitivity of detection of

  2018-11-14

  

  In the present study, the sensitivity of detection of the clinical isolates in vitro by the FcMBL ELLecSA was enhanced upon release of PAMPs by either mechanical disruption or treatment with bacteriocidal antibiotics, and this correlated with the detection of PAMPs in blood samples in both our studi

• We also found that q does not

  2018-11-14

  

  We also found that 1q+ does not show preference in evolutionary timing—it may occur as an early or late event—which suggests that its oncogenic effect is independent of other genetic changes. Therefore, we suspect that 1q+ may have a similar effect on WT outcome regardless of whether it is homogeneo

• We found that smoking cessation is beneficial in reducing an

  2018-11-14

  

  We found that smoking cessation is beneficial in reducing and delaying lung cancer and this beneficial effect does not vary with CHRNA5 rs16969968, which is a genetic marker for nicotine dependence (Liu et al., 2010; Saccone et al., 2010; TAG, 2010; Thorgeirsson et al., 2010), lung cancer (Amos et a

• To determine if the overexpression of miR negatively

  2018-11-14

  

  To determine if the overexpression of miR-137 negatively regulate EFNB2 expression, human neuroblastoma SH-SY5Y cells were transfected with mature miR-137 sequences or negative control miRNAs. The results showed that the overexpression of miR-137 did not affect the mRNA expression of EFNB2 but signi

• Our mouse model is also useful for

  2018-11-14

  

  Our mouse model is also useful for studying ZIKV\'s tissue tropism and potential complications of severe ZIKV infection. In addition to the reported findings of detectable virus particles and/or RNA in the brain, spinal cord, kidney, spleen, liver, testis, ovary, heart, lung, muscle, and blood of ty

• A second interesting conclusion that can be

  2018-11-14

  

  A second interesting conclusion that can be drawn from our work concerns the paradoxical effect of PIO on Hq versus WT mice. PIO, a widely used hypoglycaemic drug, acted as predicted for a PPARγ ligand in WT mice, therefore decreasing glycaemia and weight, without significantly affecting motor perfo

• br Methods The study covered vaccinations and survival of al

  2018-11-14

  

  Methods The study covered vaccinations and survival of all children born within the Matlab HDSS between 1986 and 1999 and with follow-up to December 31, 2001. The previous study analysed the role of vaccination for child survival between 6weeks and 9months of age when MV is supposed to be given a

• The depleted RNA was fragmented using

  2018-11-14

  

  The depleted RNA was fragmented using RNase III in preparation for amplification of the cDNA library, which was produced by reverse transcription from adapters attached to the ends of the RNA molecules, in accordance with the SOLiD™ Total RNA-Seq kit protocol (Life Technologies™, CA). Next, 6% denat

• br Data The data presented in

  2018-11-14

  

  Data The data presented in this article is related to the research article entitled “Longitudinal multiple sclerosis lesion segmentation: Resource and challenge\" [1]. The data consists of magnetic resonance (MR) images (MRI) divided into two cohorts: 1) Training Set; and 2) Test Set. The Trainin

• br Data Here we described the synergistic

  2018-11-14

  

  Data Here, we described the synergistic anti-tumor effects of Selaginella tamariscina extract and amentoflavone combined with the doxorubicin hydrochloride treatment in mice. The combinatorial effects of Selaginella tamariscina extract (Fig. 1A) or amentoflavone (Fig. 1B) on the anti-tumor action

• The present study tested whether children with recent

  2018-11-14

  

  The present study tested whether children with recent-onset tics are capable of suppressing their tics and if so, whether an environmental contingency (namely, reward) modifies this ability. Given evidence that reward can enhance inhibitory control in children without tics (Padmanabhan et al., 2011;

• According to the one dimensional stress wave theory

  2018-11-13

  

  According to the one-dimensional stress wave theory, the train , stress and strain rate of the specimen can be calculated by two-wave methodwhere and are the time-resolved reflected and transmitted strains in the incident and transmission bars with cross-sectional area A; E is the Young\'s modul

• La sentencia marca un hito Luego de se

  2018-11-13

  

  La sentencia marca un hito. Luego de señalar que el asunto es complejo porque está envuelto en una problemática social y jurídica profunda, pues las personas que prestan su trabajo como sexo servidoras/es se encuentran en la mayoríade los casos en una situación de vulnerabilidad extrema que cargan A

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