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There remains controversy however as to
2018-10-25
There remains controversy, however, as to the precise mechanism of genesis of such phenotypes (Cieslewicz et al., 1999). One of the major stumbling blocks here is lack of data concerning the kinetics of lung granulocyte immigration and emigration in asthma. Studies addressing the differential migrat
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Mature miRs act by destabilising mRNAs with some degree
2018-10-25
Mature miRs act by destabilising mRNAs with some degree of complementarity or by repressing protein translation, leading to down regulation of target genes and changes in biological functions (Bohnsack et al., 2004; Chen and Rajewsky, 2007; Kim, 2005; Lee et al., 2003). The expression of miRs is tig
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In spite of these interesting observations
2018-10-25
In spite of these interesting observations, some additional questions arise from the study. For example, consistent with previous reports, circadian phase and period length are influenced by diet (). However, here the HFD has the general effect in WT mice of shortening period length rather than leng
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The estimates of cancer free survival for the
2018-10-25
The estimates of cancer-free survival for the groups with 10-min adenylate cyclase levels below and above the median showed an increasing divergence over the 40-year follow-up (Fig. 2). Thus, it is unlikely that causal factors related to glucose disposal at baseline were temporary in nature. It is
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Translational approaches to targeting the biological
2018-10-25
Translational approaches to targeting the biological basis of aging is a rapidly-developing field. discuss targeting cellular senescence programs to improve fitness. Among these approaches are so-called senolytic agents, which selectively clear senescent xanthine oxidase inhibitor and relieve the
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One of the limitations of this study is the differences
2018-10-25
One of the limitations of this study is the differences in the patient populations between the two CRC patient cohorts. As shown in Table 1 and 2, there were differences in the number of patients with stage IV CRC between cohort 1 and cohort 2. At first, we validated the clinical significance of SNO
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br Acknowledgements Many thanks to C Johnson for providing u
2018-10-25
Acknowledgements Many thanks to C. Johnson for providing unpublished data. This research was supported by an Australian Postgraduate Award and Australian Government Caring for our Country 2 Target Area Grant 2013/14 (Project ID: TAG14-00542) Bettongia tropica population status, viability and impa
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br Materials and methods br Results br Discussion
2018-10-25
Materials and methods Results Discussion With the use of fNIRS we were able to measure localized urokinase responses to visual and auditory social cues across the first two years of life. For the visual social versus non-social contrast, the response was remarkably consistent across 4–24 mo
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The relationship between the static
2018-10-25
The relationship between the static unbalance and the tilt angle is given by McCoy [8] as follows The lateral throw-off due to the bullet tilt at the muzzle is computed using the following equation derived in McCoy [8] Substituting Eq. (10) into Eq. (11), one gets the lateral throw-off due to the
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Han sido numerosas las cr
2018-10-25
Han sido numerosas las críticas y objeciones interpuestas al razonamiento de Money (por mencionar algunos: Diamond y Sigmundson 1997; Kessler 1998; Butler, 2001 [en este volumen]; Chase 2005; Cabral 2006 y 2009). Teóricos, metodológicos, políticos y éticos, los señalamientos apuntan ap-1 transcripti
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Al igual que en cualquier otro
2018-10-25
Al igual que en cualquier otro empleo, oficio o profesión, del trabajo sexual se extrae plusvalía. Solo que la explotación de una actividad de servicios que se encuentra al margen de la regulación laboral se da sin derechos laborales y con formas que generan exclusión y violencia. En el discurso de
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Increase in foreign direct investment FDI may
2018-10-25
Increase in foreign direct investment (FDI) may decrease foreign portfolio investment volatility because it enhances the confidence of foreign investors and brings more investment in the home country (Gozgor & Erzurumlu, 2010). Similarly, Iyer, Rambaldi, and Tang (2003) found that FDI caused FPI whi
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Sirolimus The most common mechanism of colistin
2018-10-25
The most common mechanism of colistin resistance is modification of LPS, a component of cell membrane, which is the first site of action of colistin. To determine whether inner and outer membranes were still present or intact in Col-R and Col-D A. baumannii strains, we visualized the 2 Col-S, 2 Col-
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All these claims led to the
2018-10-24
All these claims led to the paradoxical situation whereby the heart, previously described as a non-renewing organ, has turned into the organ with the highest number of distinct types of resident stem/progenitor cells. However, aside from the Isl-1pos cardiac progenitor cells, which are direct progen
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br Design of donor plasmids If no footprintless
2018-10-24
Design of donor plasmids If no footprintless gene targeting is required or it is intended to introduce larger transgenes, donor plasmids have to be constructed that contain the homology arms flanking the transgenes or selection cassettes coupled to promoters of choice. Similarly, donor plasmids c
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