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br Methods br Results br Discussion Originally human bone ma
2018-10-31
Methods Results Discussion Originally, human bone marrow-derived CD34+ mao inhibitor were defined as hematopoietic stem/progenitor-rich cells, while endothelial progenitor cells (EPCs), which play an important role in post-natal angiogenesis/vasculogenesis in ischemic tissues, have also be
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Altogether this study shows as proof
2018-10-31
Altogether, this study shows as proof of principle that conversion of fibroblasts toward a neural cell fate can be achieved solely by small molecule treatment. We identified CB as potent compound to induce neural cell identity and developed a CB-based approach to efficiently generate Schwann hippo s
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Unlike the LMW FGF isoform which
2018-10-31
Unlike the LMW FGF2 isoform, which is well-studied, the HMW isoforms of FGF2 are not nearly as well-understood, but recent reports have investigated the effects of HMW FGF2 signaling in various contexts. Localization of FGF2 isoforms can vary depending on cellular conditions and stimuli (Arese et al
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Herein we observed increased SEMA A gene expression in
2018-10-31
Herein, we observed increased SEMA3A gene expression in BMSCs of all patients compared to the control group. In the literature, we found two studies of SEMA3A in AML: The first reported that epigenetic changes increases SEMA3A expression and contributes to EZH2 silencing in patients with secondary A
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br Conclusions The following are the supplementary data rela
2018-10-31
Conclusions The following are the supplementary data related to this article. Conflict of interest Acknowledgements This work was supported by The Danish Cancer Society (R.C. Grant number DP07024); Kgl. Hofbundtmester Aage Bang Fund (Grant number 55-07/08); Karen Elise Jensen Fund; Karen K
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order (±)-Nutlin-3 Pacemaking in SAN cells is a complex
2018-10-31
Pacemaking in SAN order (±)-Nutlin-3 is a complex process, explained by a combination of ion fluxes across the sarcolemmal membrane and the SR, designated as the calcium and membrane clocks (Lakatta et al., 2010). The mechanisms of spontaneous beating in hiPSC-CM are not well understood. Previous st
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Introduction The majority of induced pluripotent stem cells
2018-10-31
Introduction The majority of induced pluripotent stem cells (iPSCs) are not fully reprogrammed (Chan et al., 2009; Lee et al., 2013; Mikkelsen et al., 2008). There is still minimal information on transition checkpoints necessary to induce full reprogramming. Pluripotent stem cells (PSCs) have funct
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Thematic synthesis was used to identify important and recurr
2018-10-30
Thematic synthesis was used to identify important and recurrent themes (conducted in 2015) (Thomas & Harden, 2008). This method was developed based on the qualitative analytical technique ‘thematic analysis’ and borrows from traditional systematic review methods. It was developed with the aim that t
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In many ways religiosity is easier to quantify than spiritua
2018-10-30
In many ways, religiosity is easier to quantify than spirituality. Because of the abstraction involved with the concept, survey research often includes indirect indicators of spirituality, such as the item referred to in Table 1. This type of measure demonstrates the broadness of spirituality. In so
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The deterioration in birth outcomes
2018-10-30
The deterioration in birth outcomes is primarily evident in the incidence of low birth weight; even when analyzing differences in birth weight, the coefficients are always negative and larger in magnitude compared with those of second-generation immigrants. The average incidence of low birth weight
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Recently due to the unique
2018-10-30
Recently, due to the unique physicochemical properties, excellent biocompatibility and biodegradability, polydopamine nanoparticles (PDA NPs) have attracted much attention and been extensively investigated for various applications including surface modification, bio-inspired hydrogel generation, bio
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R406 The changes in signal for
2018-10-30
The changes in signal for a radiation-sensitive metal–oxide–semiconductor-field-effect transistor (RADFET, also known as MOS dosimeter), upon detection of R406 induced charges, is intrinsically amplified due to the field effect operation mechanism. RADFET based SSD have been touted as a direct conve
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El escepticismo se gest a lo largo de
2018-10-30
El escepticismo se gestó withaferin a Supplier lo largo de los últimos 15 años del siglo pasado, cuando debido a la crisis del petróleo y la deuda externa se llevó a cabo la primera generación de reformas, todas de tipo macroeconómico: estabilización, finanzas públicas, privatización de empresas par
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Como se mencion al inicio del art culo
2018-10-30
Como se mencionó al inicio del artículo, el más importante impuesto que administran los gobiernos locales es el impuesto SBI-0206965 la propiedad o predial; mientras que impuestos a las ventas (IVA) y al ingreso (ISR) son controlados por el gobierno central, estos últimos ingresos se comparten entre
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Los desequilibrios externos al interior de la zona euro se
2018-10-30
Los desequilibrios externos al interior de la zona euro se explican por tres factores interrelacionados. Por una parte, la heterogeneidad de la estructura productiva de los países de la eurozona, que se acentuó con la adopción del euro como moneda comunitaria, provoca que haya importantes diferencia
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