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At the mechanistic level our results strongly suggested
2019-06-28
At the mechanistic level, our results strongly suggested that the cholestatic protective effect of STS was most likely accounted for by the activation of LXR, a nuclear receptor known for its anti-cholestatic activity. The activation of LXR was supported by the induction of typical LXR target genes,
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br Discussion We evaluated and determined the
2019-06-27
Discussion We evaluated and determined the incidence and severity of subjective reports of dyspepsia symptoms due to dabigatran. Based on the results of the RE-LY trial [4], the AE that was significantly more common with dabigatran than with warfarin was dyspepsia. In the sub-group (326 Japanese
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br Conclusion br Financial support This research was
2019-06-27
Conclusion Financial support This research was supported by a grant from the ׳Gerencia de Salud, Consejería de Sanidad, Junta de Castilla y Leon׳ [GRS 308/A/08] and ‘Caja Burgos Foundation’ [Convocatoria 2007].The funding organization had no involvement in the study. Clinical trial registra
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br Acknowledgments We thank all the
2019-06-27
Acknowledgments We thank all the ultramarathon runners who participated in this study and all the doctors, nurses, and emergency medical technicians who provided professional care at the ultramarathon race. We also thank our colleagues at Soochow University, Taipei, Taiwan and the Chinese Taipei
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br Conflict of interest br
2019-06-27
Conflict of interest Introduction Over the last several decades, substantial research interest has been focused on characterizing the pathophysiological substrate underlying atrial fibrillation (AF) [1]. AF is a complex arrhythmia and has been shown to be temporally variable, so that AF durati
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br Escribir y destacar promoci n la identidad por
2019-06-27
Escribir y destacar (promoción 1975-1985): la identidad por las diferencias ¿Cómo escribir dentro de un mercado de tantos competidores para un país de escasos lectores? En México, ni siquiera los estudiantes de la universidad consumen libros y hay más papelerías que librerías (Zaid 2013: 143-154
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Sin embargo la Relaci n no fue traducida en forma
2019-06-27
Sin embargo, la Relación no fue traducida en forma igualmente precisa por Ulloa, que nos devuelve un texto corrompido, lo cual se manifiesta en las transcripciones de los términos en la lengua indígena. Por fortuna, es posible comparar el texto italiano con otras versiones producidas durante la prim
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MTEP hydrochloride Desde la perspectiva expuesta la etnicida
2019-06-27
Desde la perspectiva expuesta, la etnicidad constituye una dimensión potencial de la identidad, fundamentada en un conjunto de elementos que, al seguir la tradición weberiana, pueden abarcar la percepción de origen, cultura, idioma o rasgos fenotípicos compartidos por un conjunto de personas. La adq
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The deletion of q seen in our patient
2019-06-27
The deletion of 14q seen in our patient included the IGH locus at 14q32.33. This is noteworthy, because loss of 14q has been reported as a recurrent aberration acquired during the natural history of CLL. The acquisition of a del(14) may thus be indicative of CLL in transformation. In a study of a la
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br A hallmark of the
2019-06-27
A hallmark of the past decade has been the remarkable progress made in reducing maternal and child mortality, an achievement credited in some measure to the Millennium Development Goals. The reduction in child deaths from an estimated 12·7 million under-5 deaths in 1990 to fewer than 6 million dea
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South Africa was the first African country to implement
2019-06-27
South Africa was the first African country to implement the seven-valent pneumococcal conjugate vaccine (PCV7) in its routine infant immunisation programme (in 2009), with the novel schedule aligned to WHO\'s recommended Expanded Programme on Immunisation (EPI)—ie, a 2 + 1 schedule with doses at age
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We have received funding from the Wellcome Trust
2019-06-27
We have received funding from the Wellcome Trust to develop a global atlas of podoconiosis. We aim to advance new knowledge on the geographical distribution and spatial epidemiology of the disease. A first step in this work will be to establish the geographical absence of disease by applying an evid
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EVP4593 molecular br CUANDO EL CUERPO SE HACE ESPACIO El pun
2019-06-26
CUANDO EL CUERPO SE HACE ESPACIO El punto en común de estos lienzos es la ausencia de mirada (figuras 3a y 3b). En el primero los ojos están negros, se presentan las dos órbitas vacías; en el segundo están deliberadamente borrados, ya que incluso se puede distinguir por debajo el contorno de los
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br Considera es finais Tentamos ainda incluir ao
2019-06-26
Considerações finais Tentamos ainda incluir ao longo do texto o trabalho de campo que se realiza na comunidade quilombola de Capoeiras, no estado do Rio Grande do Norte. É de lá que absorvemos experiências que pudemos considerar vivenciais e que tutelam os sentidos das nossas buscas teóricas e ac
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The PAX gene encodes a
2019-06-26
The PAX5 gene encodes a transcriptional factor, which is specifically expressed at the early stages of B-cell differentiation and it is required for B-cell development. Its dysregulation is involved in the leukemogenesis of B-ALL. The PAX5 gene rearrangements account for approximately 2.5% of pediat
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